I've been using MEME's for years and have seen greater interactions via social media (the perfect place to employ this method) including comments, likes and even shares!
My newest book, a Sci-fi novel, is only entering it's second draft, but already I've been creating MEME's in order to build interest. I will place these again when the book is released on my own pages, as well as related group pages across multiple networks with links to purchase the book or ebook.
Writing and marketing go side-by-side and MEME's tend to excite your potential buyer through intriguing quotes and accompanying images. MEME's can vary in size and there is no rule to follow when creating one. However, if you plan to use it as an ad on Facebook, remember not to use too many words to get your point across. FB ads limit the amount of space the copy employs on your MEME.
Below are some examples of the resent MEME's I've posted for a book which is still months out form being completed.